Cisplatin lagerung

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August undefined, 2024

WebApr 6, 2024 · Cisplatin (Platinol) is an inorganic coordination complex with a broad range of antitumor activity. It is especially useful in the treatment of testicular and ovarian cancer. It binds to DNA at nucleophilic sites, such as the N7 and O6 of guanine, producing alterations in DNA structure and inhibition of DNA synthesis.

PRODUCT INFORMATION –CISPLATIN INJECTION(CISPLATIN)

WebApr 5, 2024 · Cisplatin for injection has been administered at 20 mg/m 2 intravenously daily for 5 days per cycle. Other doses and combination regimens have been used. Advanced … WebFeb 16, 2024 · Generic name: cisplatin [ sis-PLA-tin ] Brand names: Platinol, Platinol-AQ, Platinol (Restricted Access) Dosage forms: intravenous powder for injection (50 mg), … can swine get a sinus infection

Cellular responses to Cisplatin-induced DNA damage

WebCisplatin Injection infusion concentrate is a clear, colorless, sterile aqueous solution available in amber vials. Each 50 mL or 100 mL amber vial of infusion concentrate … WebDec 12, 2024 · Cisplatin Adult Medication Share This information from Lexicomp ® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider. Warning This drug may cause kidney problems like kidney failure. WebSep 18, 2024 · Cisplatin is a medication used to manage and treat solid tumors and hematologic malignancies. It is in the alkylating agent class of cytotoxic medications. This activity reviews the indications, action, and contraindications for cisplatinum as a valuable agent in treating malignancy. can swine flu be treated

Cisplatin (Intravenous Route) Side Effects - Mayo Clinic

WebSep 27, 2024 · Cisplatin for injection, USP, a platinum-based drug for intravenous use, is a white to light yellow lyophilized powder. Each vial of Cisplatin for injection, USP … WebCisplatin is a platinum chemotherapeutic used in a variety of malignancies. The antineoplastic activity occurs from DNA cross-links and adducts, in addition to the generation of superoxide radicals. Nephrotoxicity is the most well-known and potentially most clinically significant toxicity. can swine flu be transmitted to humansWebOct 22, 2024 · Cisplatin is an alkylating agent which induces DNA damage through the formation of cisplatin-DNA adducts, leading to cell cycle arrest and apoptosis. In the management of advanced OSCC, cisplatin-based chemotherapy or chemoradiotherapy has been considered as the first-line treatment. flashback background music

"WebSep 15, 2024 · Cisplatin is a prescription medicine used to treat the symptoms of cancer in the testicles (Metastatic Testicular Tumors), bladder (Advanced Bladder Cancer) and … " - Cisplatin lagerung

Cisplatin lagerung

SUMMARY OF PRODUCT CHARACTERISTICS 1. NAME …

WebFür die Monotherapie werden die beiden folgenden Dosierungsregime empfohlen: – Einzeldosis von 50 bis 120 mg/m² Kör- peroberfläche alle 3 bis 4 Wochen – 15 bis 20 mg/m² pro Tag über fünf Tage alle 3 bis 4 Wochen. Wird Cisplatin im Rahmen einer … WebFeb 17, 2024 · Cisplatin inhibits DNA synthesis by the formation of DNA cross-links; denatures the double helix; covalently binds to DNA bases and disrupts DNA function; may also bind to proteins; the cis -isomer is 14 …

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WebJun 13, 2005 · Following cisplatin doses of 20 to 120 mg/m^2, the concentrations of platinum are highest in liver, prostate, and kidney; somewhat lower in bladder, muscle, testicle, pancreas, and spleen; and lowest in bowel, adrenal, heart, lung, cerebrum, and cerebellum. Platinum is present in tissues for as long as 180 days after the last … WebFeb 16, 2024 · Generic name: cisplatin [ sis-PLA-tin ] Brand names: Platinol, Platinol-AQ, Platinol (Restricted Access) Dosage forms: intravenous powder for injection (50 mg), intravenous solution (1 mg/mL) Drug class: Alkylating agents Medically reviewed by Drugs.com on Feb 16, 2024. Written by Cerner Multum. Uses Warnings Before taking …

WebSep 18, 2024 · Cisplatin is a medication used to manage and treat solid tumors and hematologic malignancies. It is in the alkylating agent class of cytotoxic medications. This activity reviews the indications, action, and … WebCisplatin is administered to cancer patients intravenously as a sterile saline solution (that is, containing salt—specifically, sodium chloride). Once cisplatin is in the bloodstream, it remains intact due the relatively high concentration of chloride ions (~100 mM).

WebDie Heilwirkung erfordert eine von der Tumorart und Fraktionierung abhängige Gesamtdosis von 20 bis 80 Gray, die in Abhängigkeit vom Behandlungsschema in einer Sitzung oder über mehrere Wochen verteilt verabreicht wird. WebFeb 1, 2024 · Cisplatin injection is used to treat advanced cancer of the bladder, ovaries, or testicles. Cisplatin is an antineoplastic agent (cancer medicine). It interferes with the …

WebCisplatin adducts are Guanine-Guanine (GG) DNA intrastrand cross links caused by the chemical compound Cisplatin. Cisplatin is used as a chemotherapy agent that contains …

WebJun 13, 2005 · Cisplatin, cisplatinum or cis-diamminedichloroplatinum (II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including … can swings be hung from chinese tallow treesWebCisplatin is administered through a vein (intravenously or IV) as an infusion. There is no pill form of cisplatin. Cisplatin is an irritant. An irritant is a chemical that can cause … flashback badge youtubeWebCisplatin Injection is a sterile, isotonic, preservative free solution containing cisplatin 1mg/mL. For the full list of excipients, see Section 6.1 List of excipients. 3. … flashback bachelorette 2022WebApr 1, 2016 · By using two pairs of genetically matched cisplatin-sensitive and cisplatin-resistant ovarian cancer cell lines, we tested the hypothesis that downregulating hypoxia-inducible factor-1 (HIF-1), which regulates metabolic enzymes involved in glycolysis, is a promising strategy for overcoming cisplatin resistance of human ovarian cancer cells. flashback band ashevilleWebCisplatin for injection is a highly emetogenic antineoplastic agent; premedicate with anti-emetic agents; without antiemetic therapy, marked nausea and vomiting occur in almost all patients treated with cisplatin … can swings breakWebexperienced nephrotoxicity as a result of cisplatin therapy. The carcinogenic potential of carboplatin has not been studied but compounds with similar mechanisms of action and … flashback a table in oracleWebCisplatin is an antineoplastic drug used for the treatment of cancer patients with a variety of different malignancies. Application Cisplatin may be used as an analytical reference standard for the determination of the analyte in plasma, cancer cell, and tumor samples by high-performance liquid chromatographic assay. flash back baixar