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Cthrc1 cancer

WebMar 21, 2024 · Bioinformatics method. LUAD related data sets were acquired from Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA), as shown in Table 1.Expression differences of CTHRC1 between normal tissue and LUAD tissue were tested by t-test, and the effect of CTHRC1 expression on patient’s prognosis was detected with … WebCTHRC1 has a role in pancreatic cancer progression and metastasis by regulating migration and adhesion activities of cancer cells. PMID: 23222813; Data indicate that the upregulated expression of collagen triple helix repeat containing 1 (CTHRC1) in gastric carcinogenesis contributes to tumor cell invasion and metastasis.

CTHRC1 promotes liver metastasis by reshaping infiltrated

WebJun 20, 2024 · CTHRC1 is a secretory glycoprotein that was discovered while differentially expressed genes were screened after severe arterial injury in rats. 6,7 Subsequently, researchers reported that CTHRC1 is … WebOct 26, 2024 · The function of collagen triple helix repeat containing 1 (CTHRC1) as an oncogene has been reported in a growing number of publications. Bioinformatics methods represent a beneficial approach to examine the mechanism and function of the CTHRC1 gene in the disease process of cancers from a pan-cancer perspective. In this study, … granulomata of the spleen https://oakwoodlighting.com

CTHRC1 is a Potential Prognostic Biomarker and Correlated with ...

WebCollagen triple helix repeat containing 1 (CTHRC1) is a secreted glycoprotein that decreases the deposition of collagen matrix and accelerates tumor metastasis. However, the relationship between CTHRC1 and the outcomes of head and neck squamous cell carcinoma (HNSCC) and tumor‑infiltrating lymphocytes remains unclear. In the present … WebIdentification and Verification of Potential Biomarkers in Gastric Cancer By Integrated Bioinformatic Analysis. Chenyu Sun, Yue ... Collagen Type X Alpha 1 Chain (COL10A1), … WebMar 1, 2024 · Collagen triple helix repeat containing 1 (CTHRC1) is a glycosylated protein secreted during tissue repair, which reduces collagen matrix deposition and … granulomatosis infantiseptica is caused by

The Role of CTHRC1 in Regulation of Multiple Signaling …

Category:CTHRC1 Gene - GeneCards CTHR1 Protein CTHR1 …

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Cthrc1 cancer

CTHRC1 is a potential prognostic biomarker in breast …

WebJul 19, 2024 · Abstract. Collagen triple helix repeat containing-1 (CTHRC1), highly expressed in multiple human solid tumors, has been identified as a tumor associated … WebFeb 15, 2024 · In CRC, the deletion of SMAD4 in cancer cells resulted in a decrease in S100A8+ monocytes in the tumor microenvironment . Furthermore, the release of Collagen Triple Helix Repeat Containing 1 (CTHRC1) by CRC cells induced M2 polarization of TAMs through TGFβ signaling and further promoted hepatic metastasis in mouse models …

Cthrc1 cancer

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WebCollagen triple helix repeat containing-1 (CTHRC1) has been identified as cancer-related protein. CTHRC1 expresses mainly in adventitial fibroblasts and neointimal smooth muscle cells of balloon ... WebJ Cancer 2016; 7(15):2213-2220. doi:10.7150/jca.16539 This issue Cite. Review. Multidimensional Roles of Collagen Triple Helix Repeat Containing 1 (CTHRC1) in Malignant Cancers . Neng Jiang 1*, …

WebCollagen triple helix repeat containing 1 is a protein that in humans is encoded by the CTHRC1 gene. Function. This locus encodes a protein that may play a role in the cellular response to arterial injury through involvement in vascular remodeling. Mutations at this locus have been associated with Barrett's esophagus and esophageal adenocarcinoma. WebOct 22, 2024 · The association of CTHRC1 with tumor progression is demonstrated in various human cancers, including hepatocellular carcinoma, gastric cancer, pancreatic cancer, GIST and colorectal cancer (1-3).In a meta-analysis done by Wang et al., the results revealed correlation of CTHRC1 expression with TNM stage in gastric cancer, …

WebMar 30, 2012 · The gene, collagen triple helix repeat containing 1 (CTHRC1), has been reported to increase in several kinds of human solid cancers and is associated with tumor invasion and metastasis.To date, the expression and function of CTHRC1 in gastric cancer (GC) have not been reported. WebMar 21, 2024 · Single-Cell RNA Sequencing Analysis Reveals a Crucial Role for CTHRC1 (Collagen Triple Helix Repeat Containing 1) Cardiac Fibroblasts After Myocardial …

WebSep 28, 2024 · CTHRC1, collagen triple helix repeat containing-1; CAF, cancer-associated fibroblast; CM, conditioned media. CAFs promote EMT alterations in BC cells by secreting CTHRC1 EMT is a recognized biological process that plays a key role in tumor metastasis, and is characterized by the loss of epithelial markers (such as E-cadherin) …

WebThis study aimed to investigate the prognostic value of CTHRC1, and further explore its association with immune infiltration in breast cancer. Javascript is currently disabled in … chippenham crimeWebOct 6, 2024 · In the current study, we comprehensively analyzed CTHRC1 in distinct human cancer subtypes for the first time and find more closely CTHRC1-associated cancer … granuloma toothWebNov 29, 2024 · Background This study aimed to investigate the prognostic value of the potential biomarker collagen triple helix repeat containing 1 (CTHRC1) in lung … chippenham doctorsWebFeb 22, 2007 · We originally identified collagen triple helix repeat containing-1 (Cthrc1) in a screen for differentially expressed genes in normal versus balloon-injured arteries. 1 In … granulomatosis on ctgranulomatosis in the lungsWebMay 13, 2024 · Here, by comparing the gene expression patterns in primary colorectal cancer (CRC) patients with or without metastasis, we found … granulomatosis with polyangiitis ancaWebJun 20, 2024 · This study aimed to investigate the prognostic value of CTHRC1, and further explore its association with immune infiltration in breast cancer. Methods: CTHRC1 … granulomatosis with polyangiitis amboss