Gingival hyperplasia phenytoin
WebIn our study, we evaluate the effect of phenytoin, a drug whose active substance is phenytoin, on gingival fibroblasts of healthy volunteers. Gene expression of 29 genes …
Gingival hyperplasia phenytoin
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WebGingival overgrowth may be an adverse effect of various systemic medications. It is best recognized in association with phenytoin, cyclosporine, and nifedipine, although associations with other anticonvulsants, immunosuppressants, and calcium channel blockers have been noted as well. Also, some studies have implicated oral … WebDrug-induced gingival overgrowth is a side effect associated principally with 3 types of drugs: anticonvulsant (phenytoin), immunosuppressant (cyclosporine A), and various calcium channel blockers (nifedipine, verapamil, diltiazem). In this review, we describe the features of phenytoin-, cyclosporin …
WebMay 19, 2011 · Pathogenesis of phenytoin-induced gingival overgrowth.Several mechanisms are involved in the development of gingival overgrowth. Phenytoin induces a decrease in the Ca 2+ cell influx leading to a reduction in the uptake of folic acid, thus limiting the production of active collagenase. The drug decreases collagen endocytosis … WebFeb 26, 2024 · 1. Inflammatory gum enlargement. Gingival hyperplasia can occur as a direct result of inflammation. The inflammation is often caused by plaque buildup on the teeth from food, bacteria, and poor ...
WebMar 26, 2024 · Several causes of gingival hyperplasia are known, and the most recognized is drug-induced gingival enlargement. Furthermore, causes of congenital gingival enlargement include hereditary and metabolic disorders, such the fetal valproate syndrome. ... Langerhans cells in human chronic gingivitis and phenytoin-induced … WebOct 30, 2024 · Gingival enlargement is a term now used to describe medication-related gingival overgrowth or gingival hyperplasia, a common reactionary phenomenon that occurs with use of several types of therapeutic agents, including AEDs. 2 This disorder has been recognized since 1939, shortly after the introduction of PHT.
WebSep 19, 2024 · Drug-induced gingival overgrowth (DIGO), also referred to as drug-induced gingival enlargement, and previously known as drug …
WebFeb 3, 2000 · Gingival Hyperplasia Induced by Phenytoin. Figure 1. A 17-year-old boy had generalized tonic–clonic seizures for four years. When the seizures began, a … propo eturauhassyöpäyhdistysWebDrug-induced gingival enlargement was first observed in patients who were taking phenytoin for epilepsy, with approximately 50% having gingival overgrowth. … propionaatti valkoinenWebGingival hyperplasia is a condition when the gum tissue becomes enlarged and gingival cells increase in number. First documented in dental literature in 1939 as a side effect of phenytoin, this condition starts with a mild swelling or enlargement that, if left untreated, progresses rapidly. propitiation 1 john 2:2WebNon-inflamed gingival enlargement tends to be a darker red or purple. It may be soft, which bleeds easily, or firm and fibrous. It is also more likely to occur in those with poor dental hygiene. Causes include: Medications, … proportion yvan monkaWebMar 26, 2024 · Drug-induced gingival overgrowth, also known as gingival hyperplasia secondary to drugs, was first reported in the dental literature in the early 1960s in … propissaWebGingival hyperplasia or gingival overgrowth is a common occurrence in patients taking phenytoin, cyclosporine, or calcium channel blockers. … propolis kaufen rossmannWebGingival overgrowth (GO), hypertrophic gingivitis, gingival hyperplasia, gingival hypertrophy: Gingivitis, a common cause of inflammatory gingival enlargement. ... Of all cases of DIGO, about 50% are attributed to phenytoin, 30% to cyclosporins and the remaining 10-20% to calcium channel blockers. propolmannan uk