Web11 apr. 2024 · Neonatal rat cardiomyocytes are often used to study cardiac myocyte hypertrophy. They respond to pharmacological ( Shubeita et al., 1990 ; Knowlton et al., … WebThere was a regular histomorphology of cardiomyocytes, interstitium, and blood vessels in treated rats compared to untreated HpCM rats which expressed hypertrophic cardiomyocytes, with polymorphic nuclei, prominent …
Cardiac Hypertrophy: Molecular and Cellular Events
Web11 apr. 2024 · Background: α-Melanocyte-stimulating hormone (α-MSH) regulates diverse physiological functions by activating melanocortin receptors (MC-R). α-MSH is predominantly expressed in the pituitary gland, but it is also found in several peripheral tissues such as the skin and heart. However, the role of α-MSH and its possible target … Web3 jun. 2024 · Hypertrophic cardiomyopathy (HCM) is a fatal heterogeneous myocardial disease, caused by autosomal dominant sarcomeric gene mutations, which … raissa maritain wiki
Postnatal Ablation of Foxm1 from Cardiomyocytes Causes Late
Web28 jan. 2024 · Angiotensin II (AngII) has potent cardiac hypertrophic effects mediated through activation of hypertrophic signaling like Wnt/β-Catenin signaling. In the current study, we examined the role of protein arginine methyltransferase 7 (PRMT7) in cardiac function. PRMT7 was greatly decreased in hypertrophic hearts chronically infused with … Web11 apr. 2024 · Overexpression in cardiomyocytes of AKAP79 or Cain/Cabin, molecules that associate with the calcineurin catalytic subunit and inhibit activity, blunts both phenylephrine- and angiotensin II-induced hypertrophy. 24 These results were extended in vivo, where transgenic overexpression of Cain/Cabin resulted in attenuation of both … Web10 mrt. 2024 · Aims Hypertrophic cardiomyopathy (HCM) is characterized by cardiomyocyte hypertrophy and disarray, and myocardial stiffness due to interstitial fibrosis, which result in impaired left... dacor oven control panel problems