Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 at region 3, … Skatīt vairāk Residing primarily across lysosomal membranes, these glycoproteins consist of a large, highly glycosylated end with N-linked carbon chains on the luminal side of the membrane, and a short C-terminal tail exposed to the Skatīt vairāk LAMP1 and LAMP2 glycoproteins comprise 50% of all lysosomal membrane proteins, and are thought to be responsible in part for maintaining lysosomal integrity, pH and catabolism. … Skatīt vairāk • Chang MH, Karageorgos LE, Meikle PJ (2003). "CD107a (LAMP-1) and CD107b (LAMP-2)". Journal of Biological Regulators and Homeostatic Agents. 16 (2): 147–51. PMID 12144129. • Schleutker J, Haataja L, Renlund M, Puhakka L, Viitala J, Peltonen L, … Skatīt vairāk LAMP1 expression on the surface of tumor cells has been observed for a number of different cancer types, particularly in highly metastatic … Skatīt vairāk • Cluster of differentiation Skatīt vairāk • LAMP1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • PDBe-KB provides an overview of all the structure information … Skatīt vairāk TīmeklisTo examine whether LAMP1 is a sensitive marker for assessing lysosomal defects in neurodegenerative diseases, we coimmunostained ventral root motor neurons of both WT and fALS-linked hSOD1 G93A mice at P80 with antibodies against LAMP1, …
How do we label endosomes? ResearchGate
TīmeklisThe enhanced autophagic degradation of proteins, e.g., AQP2, is shown to be an early event in hypokalemia-induced NDI, as AQP2 is seen to co-localize with autophagosomes (LC3 as a marker) and autophagolysosomes (LAMP1 as a … TīmeklisIncreased LAMP1 immunoreactivity is observed in neurons and glial cells surrounding senile plaques in Alzheimer's Disease (AD) cases, and is localized in medullary epithelial cells, single macrophages and … feliberto ramirez toro
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TīmeklisMouse monoclonal LAMP1 antibody [H4A3]. Validated in WB, IHC, ICC/IF, Flow Cyt (Intra) and tested in Human. ... Microtubule Marker (Alexa Fluor® 594) – pseudo-colored red) overnight at +4°C. The secondary antibody (pseudo-colored green) was a Goat … Tīmeklis2024. gada 3. sept. · To examine whether LAMP1 is a sensitive marker for assessing lysosomal defects in neurodegenerative diseases, we coimmunostained ventral root motor neurons of both WT and fALS-linked hSOD1 G93A mice at P80 with … TīmeklisLAMP1 (lysosomal associated membrane protein 1) and LAMP2 are distributed among autophagic and endolysosomal organelles. Despite widespread distribution, LAMP1 is routinely used as a lysosome marker and LAMP1-positive organelles are often … feliben 35 mg