WebFeb 26, 2024 · Poly(rC) binding protein 2 (PCBP2) is an RNA-binding protein that contributes to mRNA stabilization, translational silencing and enhancement and it has been implicated as a promoter of gastric cancer growth. In the present study, ... WebThe hepatitis C virus (HCV) co-opts numerous cellular elements, including proteins, lipids, and microRNAs, to complete its viral life cycle. The cellular RNA-binding protein, poly(rC)-binding protein 1 (PCBP1), was previously reported to bind to the 5′ untranslated region (UTR) of the HCV genome; however, its importance in the viral life cycle has remained …
Poly(rC)-binding protein 1 represses ferritinophagy-mediated ...
WebMay 11, 2024 · Poly(rC)-binding protein1 (PCBP1) is an RNA-binding protein that regulates mRNA stability, splicing, and translation. PCBP1 is a tumor suppressor and can inhibit the translation of several oncogenic genes. ... Poly(rC) binding protein 1 represses the translation of STAT3 through 5' UTR. @article{Li2024PolyrCBP, title={Poly ... WebMar 3, 2009 · The poly(C)-binding proteins (PCBPs) are characterized by high affinity for, and sequence-specific interaction with polycytosine, poly(C). In mammalian cells, these PCBPs belong to one of two subsets: hnRNP K/J, or the alpha-complex proteins (e.g., PCBP1-4) []. hnRNP K, PCBP1, and PCBP2 have been studied in the greatest detail.The latter two … cane's sj
Poly(rC) Binding Protein 1 Represses the Translation of STAT3
WebA protein covalently linked to poliovirus genome RNA. Proc Natl Acad Sci U S A. 1977 Jan; 74 (1):59–63. [PMC free article] [Google Scholar] Leffers H, Dejgaard K, Celis JE. Characterisation of two major cellular poly(rC)-binding human proteins, each containing three K-homologous (KH) domains. Eur J Biochem. 1995 Jun 1; 230 (2):447–453. WebFeb 28, 2024 · The hepatitis C virus (HCV) co-opts a number of cellular elements – including proteins, lipids, and microRNAs – to complete its viral life cycle. The cellular RNA-binding protein poly(rC)-binding protein 1 (PCBP1) had previously been reported to bind the HCV genome 5’ untranslated region (UTR), but its importance in the viral life cycle has … WebJun 14, 2024 · Poly(rC)-binding protein 1 (PCBP1) is a multifunctional protein that coordinates both RNA and iron. PCBP1 was initially identified as a component of … cane smoke