WebFeb 10, 2024 · The benefits of ovarian function suppression were sustained long term for premenopausal women with hormone receptor–positive breast cancer, according to updates from SOFT and TEXT, two randomized, controlled trials, presented at the 2024 San Antonio Breast Cancer Symposium. 1. A separate large meta-analysis of four randomized trials in … WebApr 20, 2024 · Purpose: The Tamoxifen and Exemestane Trial (TEXT)/Suppression of Ovarian Function Trial (SOFT) showed superior outcomes for premenopausal women with …
An Italian Delphi study to evaluate consensus on adjuvant …
WebSOFT and TEXT are complementary trials, conducted over the same period of time and on the same patient population. Patients were randomly assigned in the following treatment groups: - tamoxifen alone - tamoxifen combined with ovarian function suppression (OFS) - exemestane combined with OFS. WebDec 11, 2014 · In 2003, the International Breast Cancer Study Group (IBCSG) initiated two randomized, phase 3 trials, the Suppression of Ovarian Function Trial (SOFT) and the … cypress bay boys soccer schedule
Ovarian Suppression in Adjuvant Endocrine Therapy for …
WebDana-Farber's Meredith Regan, ScD presented an update on the SOFT/TEXT clinical trials at the 2024 San Antonio Breast Cancer Symposium WebThe SOFT and TEXT clinical trials produced practice changing results in the treatment of breast cancer in young women, who may have a poorer long-term prognosis. The research … WebJan 9, 2024 · The international randomised SOFT/TEXT clinical trials – together involving 5,738 patients from 510 hospitals and cancer centres linked to 13 BIG groups in 27 countries – were developed in parallel to test the optimal adjuvant endocrine treatment in premenopausal women with hormone-sensitive early breast cancer. SOFT and TEXT are … binary alphabet charming